Postdoctoral Training Opportunities

Cures don't just happen. St. Jude Children's Research Hospital is committed to the education and training of the next generation of research scientists. St. Jude trainees are able to learn from clinical and basic science investigators who work in close proximity and interact regularly to translate scientific discoveries into improved therapies for children.


If you are a highly motivated individual who wants to work at a world-class institution with state of the art facilities and learn from investigators at the forefront of their fields, consider advancing your research training at St. Jude.

Here are our postdoctoral research training opportunities. Please click on the position title for more information, and apply from that page if you are interested.

 

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Dr. Zhaoming Wang, a joint faculty member between St. Jude Department of Epidemiology and Cancer Control and the Department of Computational Biology, is seeking highly motivated and creative candidates for a fully supported postdoctoral fellow position to conduct high impact clinical research primarily in genetic epidemiology of cancers (childhood and subsequent adulthood cancers), biomarker discovery for treatment- and/or aging-related late effects of survivors of childhood cancer, and omics-based precision preventive medicine.   You will have the opportunity to work with large-scale whole-genome sequencing, whole-exome sequencing, epigenetic profile, and RNA sequencing data for a well-established cohort of childhood cancer survivors with clinically assessed rich set of phenotypes including subsequent neoplasms.   In this position, you will gain extensive experience and training in genetic and molecular epidemiology, as well as programming skills and analytic expertise in computational biology. You will be provided with opportunities to work within a multi-disciplinary research environment and interact with leaders in the fields of pediatric cancer, genetics, epigenetics, functional genomics, and survivorship research. The training position is supported by a V-Foundation grant for conducting social epigenomics studies in adult survivors of childhood cancer.
ID
46329
Department
Epidemiology & Cancer Control
Faculty Member
Zhaoming Wang
Postdoctoral Researcher in HPV Cancer Prevention   APPLY here for the Postdoctoral Researcher.   St. Jude Children's Research Hospital is leading the way the world understands, treats, and defeats childhood cancer and other childhood diseases. Our mission, to advancecures, and means for prevention, for pediatric catastrophic diseases through research and treatment, is at the center of our work and everything we do. We are a great place to work, consistently ranked among Fortune Magazine’s 100 Best Places to Work For®. At St. Jude, employees are encouraged to contribute new ideas, no matter who you are or what you do, to make the organization the best it can be.   We are seeking two outstanding candidates for postdoctoral fellowship positions in the HPV Cancer Prevention Program at St. Jude Children’s Research Hospital. The postdoctoral positions offer an intensive, mentored training experience in implementation science, community-engaged research, health equity, and cancer prevention through HPV vaccination. Postdoctoral fellows will be encouraged to support the research foci of the HPV Cancer Prevention Program and develop their own research programs in implementation science with a specific focus on HPV vaccination or other related topics (e.g., health equity, partner and engaged research approaches, building vaccine confidence, supporting vaccinations in clinical and community settings, public policy and advocation, communications, etc.) using implementation science frameworks.   To apply or learn more, please contact: Heather M. Brandt, PhD Director, HPV Cancer Prevention Program Member, Department of Epidemiology and Cancer Control Department of Epidemiology and Cancer Control St. Jude Children’s Research Hospital Heather.Brandt@stjude.org   Learn more about the HPV Cancer Prevention Program at stjude.org/hpv.  
ID
44854
Department
HPV Cancer Prevention
Faculty Member
Heather Brandt
Overview   Outstanding candidates are invited to apply for a medical physics postdoctoral research associate in  the Department of Radiation Oncology at St. Jude Children’s Research Hospital. In this two-year position, you will benefit from world-class resources and exceptional training in a top-ranked research environment while helping to advance treatment options for children with cancer.   Research Focus   The primary focus of this postdoctoral research associate position is on using Big Data analytics tools to improve treatment plan quality in proton therapy. We are especially interested in understanding the roles of linear energy transfer and treatment plan robustness. Research aims include the following:   - Contributing to data infrastructure efforts by reviewing clinical treatment plans, analyzing Monte Carlo dose distributions, and using good data practices   - Testing and validating novel analytics tools on curated data sets to better understand radiation therapy outcomes of children with cancer   - Investigating ways in which artificial intelligence may contribute to improving outcomes models   St. Jude offers a collaborative research environment and exceptional support for scientific discovery. The successful candidate will work closely with the principal investigators, computational scientists, and students in the research group. The postdoctoral research associate will interact with radiation oncologists, information technology support staff, clinical therapy and physics staff, and clinical scientists. Research activities will include data collection, image analysis, dosimetry comparisons with treatment planning systems and Monte Carlo calculations, experimental validation with proton beams, and report and manuscript preparation. Opportunities to gain clinical experience in proton and photon radiotherapy physics may be made available pending adequate research progress.   Resources and Equipment   As part of the Department of Radiation Oncology, the postdoctoral research associate will have access to world-class resources, including the world’s first proton therapy center with pencil-beam scanning technology that is designated solely for treating pediatric cancer, a detector-based spectral CT scanner that was the first in the world to be installed in a radiation oncology department, state-of-the-art 1.5T and 3T MR scanners, and a recently installed digital PET/CT scanner. The department also has a full suite of radiation oncology software, including Eclipse, RayStation, and Pinnacle treatment planning systems and MiM Maestro.   Contact Information   Austin M. Faught, PhD, DABR Assistant Member, Department of Radiation Oncology 262 Danny Thomas Place Memphis, TN 38105 E-mail: austin.faught@stjude.org | Web: www.stjude.org/faught
ID
44951
Department
Radiation Oncology
Faculty Member
Austin Faught
St. Jude Children's Research Hospital is committed to the education and training of the next generation of research scientists. St. Jude trainees are able to learn from clinical and basic science investigators who work in close proximity and interact regularly to translate scientific discoveries into improved therapies for children. If you are a highly motivated individual who wants to work at a world-class institution with state-of-the-art facilities and learn from investigators at the forefront of their fields, consider advancing your research training at St. Jude.   A postdoctoral position is available at St. Jude Children’s Research Hospital for an outstanding and highly motivated candidate to investigate cellular signaling in the immune system during viral infection.  We are particularly interested in dissecting the signaling pathways involved in innate immune responses and cell death (NLRs, inflammasomes) in response to viruses.  Please see the following articles: Cell (2021) 184(1)_149-168.e17. Cell (2020) 181(3):674-687.e13. Nature (2019) 573(7775):590-4. Nature Microbiology (2019) 4(2):316-27. Cell (2018) 173:1–14. Journal of Experimental Medicine (2018) 215(4):1023-34. Nature (2016) 540:583-7. Science Immunology (2016) 1(2):aag204-5. Cell (2015) 162(1):45-58. Nature Immunology (2015) 16(5):467-75. Immunity (2015) 42(4):654-64. Nature (2014) 516(7530):246-9. Nature (2013) 498(7453):224-7.    The laboratory of Dr. Thirumala-Devi Kanneganti offers a remarkable training environment for postdoctoral fellows focused on the innate immune system, including an opportunity to collaborate with researchers in the departments of Immunology, Infectious Diseases, and cancer biology. Generous salary support and a benefits package that includes professional development funds for journal subscriptions and travel to meetings are available. St. Jude Children's Research Hospital has state-of-the-art facilities including core laboratories for proteomics, microarray analysis of gene expression, transgenic/knock-out technology and animal facilities from biosafety level 2 to enhanced biosafety level 3.   Contact Information Thirumala-Devi Kanneganti, PhD Member Department of Immunology St. Jude Children’s Research Hospital 262 Danny Thomas Place Memphis, TN  38105-3678 E-mail: thirumala-devi.danneganti@stjude.org https://www.stjude.org/kanneganti
ID
44867
Department
Immunology
Faculty Member
Thirumala-Devi Kanneganti
St. Jude Children's Research Hospital is committed to the education and training of the next generation of research scientists. St. Jude trainees are able to learn from clinical and basic science investigators who work in close proximity and interact regularly to translate scientific discoveries into improved therapies for children. If you are a highly motivated individual who wants to work at a world-class institution with state-of-the-art facilities and learn from investigators at the forefront of their fields, consider advancing your research training at St. Jude.   A postdoctoral position is available at St. Jude Children’s Research Hospital for an outstanding and highly motivated candidate to investigate omics data related to innate immune signaling projects. The lab is particularly interested in dissecting signaling pathways and interactomes involved in innate immune responses and cell death (NLRs, inflammasomes). Knowledge and practical implementation of traditional machine learning and state-of-the-art deep learning techniques is essential. Understanding of working mechanisms of Alphafold2 and RoseTTAFold is highly appreciated. The tools and models built will be utilized to derive hypotheses which can be validated through in vitro and in vivo studies. Please see the following articles: Cell (2021) 184(1)_149-168.e17. Cell (2020) 181(3):674-687.e13. Nature (2019) 573(7775):590-4. Nature Microbiology (2019) 4(2):316-27. Cell (2018) 173:1–14. Journal of Experimental Medicine (2018) 215(4):1023-34. Nature (2016) 540:583-7. Science Immunology (2016) 1(2):aag204-5. Cell (2015) 162(1):45-58. Nature Immunology (2015) 16(5):467-75. Immunity (2015) 42(4):654-64. Nature (2014) 516(7530):246-9. Nature (2013) 498(7453):224-7.    The laboratory of Dr. Thirumala-Devi Kanneganti offers a remarkable training environment for postdoctoral fellows focused on the innate immune system, including an opportunity to collaborate with researchers in the departments of Immunology, Computational Biology, Infectious Diseases, and Structure Biology. Generous salary support and a benefits package that includes professional development funds for journal subscriptions and travel to meetings are available. St. Jude Children's Research Hospital has state-of-the-art facilities including core laboratories for proteomics, microarray analysis of gene expression, transgenic/knock-out technology and animal facilities from biosafety level 2 to enhanced biosafety level 3.   Contact Information Thirumala-Devi Kanneganti, PhD Member Department of Immunology
ID
44868
Department
Immunology
Faculty Member
Thirumala-Devi Kanneganti
Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital.  As a fellow you will join our faculty in the Department of Biostatistics in developing innovative statistical methods and providing statistical support for research projects at the cutting edge of biomedical and public health research.    The department is seeking an outstanding postdoc fellow to engage in the development of statistical methodology and software for complex biomedical data such as longitudinal, imaging, wearable device, and genetic/genome studies with broad application in pediatric cancer, mental health, and neurodegenerative diseases. Strong background in tensor analysis, functional data analysis, imaging data analysis, high dimensional data modeling, statistical learning, multivariate data analysis, survival data analysis, nonparametric statistics, statistical genetics, or deep learning are all considered as a plus. A recent Ph.D. in statistics, biostatistics, bioinformatics, computational biology, computer science or closely related field is required.  Appointment is for two years.  Applicants must have a strong computational background and demonstrate excellent written and verbal communication skills. For eight consecutive years, St. Jude has ranked among the top places to work in the U.S. by Forbes Magazine. Salary and benefits are very competitive. Send cover letter, CV, and three recommendation letters to Dr. Cai Li via e-mail at cai.li@stjude.org.  AA/EOE.
ID
44718
Department
Biostatistics
Faculty Member
Cai Li
Postdoctoral Research Associate in Neuroscience / Neurobiology   The Bikoff lab (https://www.bikofflab.org/) is seeking a highly motivated postdoctoral researcher interested in using quantitative approaches to behavior, in vivo calcium imaging, and optogenetics/chemogenetics to study neural circuitry in mice.   We aim to understand the functional organization of neural circuits that control movement, including how descending pathways from the brain interact with spinal circuits to implement motor output. The lab approaches this problem from multiple perspectives, using mouse genetics, single-cell transcriptomics, viral tracing and whole-brain imaging, and animal behavior to explore the role of molecularly discrete subsets of neurons in motor control. We welcome applicants from diverse backgrounds that would thrive in a highly collaborative, interactive, and supportive environment that provides the freedom to independently develop a research project.   The Bikoff lab is strongly committed to providing individual mentoring and training for all lab members, as well as additional support for career development.   Applications: Individuals with evidence of scientific accomplishment are encouraged to apply by sending their CV, a brief description of research interests, and contact information for three references to: jay.bikoff@stjude.org.
ID
44720
Department
Developmental Neurobiology
Faculty Member
Jay Bikoff
  Epigenetic Characterization and Therapeutic Discovery in Pediatric Brain Tumors   Seeking a highly motivated, organized, and responsible individual to lead a major component of our new cancer genetics and epigenetics lab, as a foundation for their career advancement in academia or industry. Candidates will leverage cancer genomics and epigenomics data that we have generated in a variety of pediatric and adult brain tumors to undertake experiments in functional discovery, validation, as well as the development of integrated large-scale datasets using new genetic technologies. The basis and funding support for this project is described in our publication Krug et al., Cancer Cell, 2019, Michaelraj et al,. Cell, 2020, and Arabzade et al., Cancer Discovery 2021. The ideal candidate will demonstrate a willingness to learn new concepts and technical skills, but most importantly harbor an enthusiasm for working in a team-based environment and interfacing with national and international collaborative efforts. An ideal candidate will have a strong foundation in molecular biology-based techniques, experience/willingness to work with animal handling and procedures, and have a willingness to learn/work with complex computational software. Our ultimate goal in the Mack Lab is to simultaneously advance science of pediatric brain tumors in addition to providing an immersive program that advances the careers of students and research fellows.   St. Jude Children’s Research Hospital is a world-renowned institution that is recognized as one of the best places to work in the nation. As a premier center for research and treatment of childhood catastrophic diseases, we employ a diverse team of scientific and healthcare professionals dedicated to the promise of hope. Children from all 50 states and from around the world have come through the doors of St. Jude for treatment, and thousands more have benefited from our research.
ID
44634
Department
Developmental Neurobiology
Faculty Member
Stephen Mack
We are seeking a highly motivated Postdoc Research Associate to join Dr. Ji Sun’s lab at St. Jude Children's Research Hospital. Successful candidates will lead research projects focusing on structural mechanisms of membrane proteins and protein machineries.  We use cryo-EM, biophysical, electrophysiological and biochemical approaches to study the function of membrane proteins and protein complexes (Sun, NSMB 2020; Sun and Mackinnon, Cell 2020; Sun and MacKinnon, Cell 2017). The lab has fully access to the state-of-the-art cryo-EM facility in St. Jude, which houses a 300kV Titan Krios and a 200 kV Talos Arctica electron microscopes, both equipped with K3 detectors. For more details, please visit https://www.stjude.org/sun or directly contact Dr. Ji Sun (ji.sun@stjude.org).
ID
44434
Department
Structural Biology
Faculty Member
Ji Sun
Postdoctoral Position in Radiation Oncology and Chemical Biology A unique postdoctoral fellow position is available immediately in the joint laboratory of Dr. Christopher Tinkle, Department of Radiation Oncology, and Dr. Anang Shelat, Department of Chemical Biology and Therapeutics, to apply state-of-the-art chemical biology and bioinformatics methodologies across diverse pediatric malignancies to investigate the molecular consequences of defective DNA repair, and to target these deficits using small molecules. This project leverages the institution’s world class repository of patient derived xenograft models and associated genomic and proteomic data sets. This work will directly support the institution’s translational program, with the goal of identifying clinically actionable drug-drug and drug-radiation combination strategies.
ID
44263
Department
Chemical Biology & Therapeutic
Faculty Member
Anang Shelat
A fully funded postdoctoral position is immediately available in the Weiss/Cheng lab in the Department of Hematology at St. Jude Children’s Research Hospital. We are looking for a candidate that are interested in therapeutic genome editing using next generation genome editors such as Base Editor or Prime editors. The candidate will study the interplay between genome editors and different types blood cells (such HSCs, other progenitors and erythroid cells) and develop and optimize novel treatment for genetic blood disorders. In this position, the candidate will gain extensive experience and training in genomics, stem cell biology, and pre-clinical study. St. Jude Children’s Research Hospital is a top-ranked Pediatric Cancer Hospital and a world-renowned basic science research institute with over 200 faculty members. St. Jude offers a highly collaborative research and training environment that includes state-of-the-art facilities and resources. Postdoctoral research fellows are provided with a competitive salary, excellent benefits, and a professional development allowance. 
ID
44222
Department
Hematology
Faculty Member
Mitchell Weiss
The Youngblood laboratory is recruiting a postdoctoral researcher to study T cell responses to chronic infections and cancer.  The project will include assessment of T cell differentiation in individuals with hematological malignancies, with opportunities to utilize animal models to investigate molecular mechanisms involved in memory T cell differentiation.
ID
44212
Department
Immunology
Faculty Member
Benjamin Youngblood
Postdoctoral Research Associate in Immunology and Immunometabolism in Dr. Hongbo Chi’s Laboratory   Immunology postdoctoral positions are available in the laboratory of Dr. Hongbo Chi in the Department of Immunology, St. Jude Children’s Research Hospital (www.stjude.org/chi), to investigate discovery and cancer immunology, by focusing on cell metabolism of the immune system (immunometabolism) and its implications in cancer and other diseases. As metabolic pathways are inextricably connected to immunity and cancer, understanding these connections allows us to gain new insights into biological concepts and disease targets. We are particularly interested in understanding the metabolic programs (e.g. glucose, lipid, and mitochondrial metabolism), signaling pathways (e.g. mTOR and Hippo kinases; metabolite- and nutrient-induced signaling), and systems-level regulatory networks (e.g. interactions between protein regulators and their targets) in basic T cell and dendritic cell biology and antitumor immunity. To this end, we apply interdisciplinary strategies by integrating immunological and genetic approaches with cutting-edge systems immunology tools, including single-cell transcriptomics, proteomics, metabolomics, network reconstruction, and in vivo CRISPR screening. Please see the following articles published over the past four years for additional information: Nature 595:724 (2021); Nature 591:306 (2021); Cell 184:1245 (2021); Cell Metabolism 32:996 (2020); Nature Reviews Immunology 20:55 (2020); Nature 565:101 (2019); Nature 576:471 (2019); Immunity 51:1012 (2019); Nature 558:141 (2018); Immunity 49:899 (2018); and Science Immunology aas9818 (2018).   St. Jude Children’s Research Hospital, ranked a best children's hospital for pediatric cancer, offers an exceptional research and training environment with state-of-the-art facilities, along with competitive salary and excellent benefits, to postdoctoral fellows.   Contact Information Hongbo Chi, PhD, Member Department of Immunology St. Jude Children’s Research Hospital 262 Danny Thomas Place Memphis, TN  38105 https://www.stjude.org/chi
ID
44139
Department
Immunology
Faculty Member
Hongbo Chi
Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital.    As a fellow you will join our faculty in the Department of Biostatistics in providing statistical support and developing innovative statistical methods for research projects at the cutting edge of biomedical research.   For eight consecutive years, St. Jude has ranked among the top places to work in the U.S. by Forbes Magazine.     Salary and benefits are competitive.  Send cover letter, CV, and three recommendation letters to Dr. Tomi Mori via e-mail at tomi.mori@stjude.org.        
ID
43885
Department
Biostatistics
Faculty Member
Motomi Mori
The Geeleher Lab is seeking outstanding candidates for a postdoctoral fellowship focused on developing innovative computational and statistical approaches to inform and improve therapies for pediatric cancer and other diseases. One of the premier pediatric research institutions in the world, St. Jude Children’s Research Hospital provides exceptional resources and a supportive environment for career development. As a postdoctoral fellow, you will interact with leaders in cancer and translational research within and outside the institution and at national/international meetings. Innovative research will be supported by the lab’s infrastructure, which includes a wet-lab component. Postdocs have considerable flexibility and freedom to develop their research programs. Current research areas - Developing machine learning approaches for integration of pre-clinical, clinical genomics and electronic health record data for drug re-purposing and pharmacogenomics of anticancer agents Identifying targeted therapies for patients with cancer is a central focus at St. Jude, and genome and RNA sequencing of patients’ tumors is now being performed regularly as part of standard-of-care. A major goal of the Geeleher lab is to explore machine learning approaches to prioritize targetable variants and expand the scope of targeted therapeutics. The postdoc will explore, optimize and build on emerging informatics techniques, including integrating somatic variation with transcriptomic variation and with protein-protein interaction networks. The Geeleher lab’s wet-lab component provides a platform for validation of computational predictions and discoveries. Successful completion of the project has the potential for a direct positive impact on patient care and high-impact publications. - Developing statistical methods for integrating single cell and bulk tissue expression data to understand the relationship between common inherited genetic variation, gene expression, and drug response Chemotherapeutic response is a complex trait influenced by numerous factors. Inherited genetic variants influencing gene expression (expression quantitative trait loci, or eQTLs) have been identified as major contributors. However, our recent work has shown that the degree of influence of eQTLs on gene expression in cancer is less well understood than previously thought. The postdoc will explore how inherited genetic variation influences cancer risk, disease progression and drug response, building on methods developed in the lab to deconvolute eQTL signals from bulk tissue expression data to specific cell types. This work will aim to improve our understanding of inherited genetic variation in cancer and yield computational approaches applicable to a broad variety of complex traits and diseases.   About the Geeleher Lab   The lab of Dr. Paul Geeleher is in the Department of Computational Biology at St. Jude Children’s Research Hospital. Dr. Geeleher is recognized for developing innovative computational approaches and has led drug repurposing efforts, spearheaded publications in Nature, Genome Research, Genome Biology, Journal of the National Cancer Institute (JNCI) and Bioinformatics in the last five years and is funded by the NIH. Postdoctoral fellows in the lab will benefit from access to the wealth of high-quality genomics data generated at St. Jude, state-of-art high-performance computing facilities, robust analytical pipelines, the latest laboratory technology, outstanding core facilities and scientific expertise in genomics, cancer biology, statistics, and computer science.
ID
43564
Department
Computational Biology
Faculty Member
Paul Geeleher
Postdoctoral Research Associate – Medicinal Chemist or Cell and Molecular Biologist   Overview We are recruiting a Postdoctoral Research Associate (either a Medicinal Chemist or a Cell and Molecular Biologist) to join the efforts in chemically modulating transcription factors. The Chen Lab (https://www.stjude.org/research/labs/chen-lab-taosheng.html) uses multidisciplinary approaches to study transcriptional regulation by nuclear receptors, including chemical biology approaches to develop chemical modulators, with a goal to understand nuclear receptor-regulated transcription networks and design therapeutic approaches to overcome drug resistance and tumorigenesis in cellular and animal models. The medicinal chemistry or cell and molecular biology efforts are expected to synergize with our pharmacology and structural biology efforts and enable publication of impactful papers (e.g., Nat Commun 8:741, 2017; J Am Chem Soc 143:18467, 2021; Nucleic Acids Res 50:3254, 2022). We work closely with the High Throughput Bioscience (HTB) Center (directed by Dr. Chen) (https://www.stjude.org/research/departments/chemical-biology-therapeutics/high-throughput-biosciences.html) on target validation, assay development, and compound screening.   The Chen Lab provides a unique training environment: in addition to basic research, the postdoctoral fellow will learn and gain experience in small molecule drug discovery from target validation, chemical probe discovery and optimization to preclinical mechanistic studies. Former Chen Lab postdocs have landed jobs as Assistant Professors in Universities, Senior Scientists in Pharmaceutical Companies, or Staff Scientists at St. Jude.   Contact Information Taosheng Chen, PhD Member (Professor), Department of Chemical Biology and Therapeutics Director, High Throughput Bioscience Center St. Jude Children's Research Hospital 262 Danny Thomas Place Memphis, TN 38105-2794 Phone: 1-901-595-5937 Email: taosheng.chen@stjude.org Website: https://www.stjude.org/chen
ID
43458
Department
Chemical Biology & Therapeutic
Faculty Member
Taosheng Chen
Changes in the Structure and Organization of the Genome During Neurogenesis   During retinal development, more than 8,000 genes change in their expression as multipotent retinal progenitor cells produce each of the 7 classes of cell types in an evolutionarily conserved birth order. Although it has been well established that multiple changes in the epigenome accompany changes in gene expression, little is known about how those processes are coordinated during neurogenesis. Over the past 5 years, we developed a detailed map of the structure and accessibility of the human and mouse retinal genome during development. Specifically, we performed a multifaceted integrated analysis that included profiling of the covalent modifications to the DNA and histones, promoter structure, chromatin accessibility, looping interactions, and euchromatin/heterochromatin localization (https://pecan.stjude.cloud/retinalnucleome). One of the most significant discoveries to come from this comprehensive analysis was the identification of a series of core regulatory circuit super-enhancers (CRC-SEs) adjacent to genes having important roles in retinal development, including Vsx2, Crx, Six3, Otx2, Fgf15, and Ascl1. Each of those CRC-SEs have been deleted in mice using CRISPR-Cas9 and analysis is ongoing. We are also analyzing the evolutionary conservation of those CRC-SEs in human stem cell derived retinal organoids. The results of these studies will be important for filling a fundamental gap in our knowledge about the role of CRC-SEs in retinal development and will set the stage for characterization of CRC-SEs in other genes required for retinogenesis. We are seeking a highly motivated postdoctoral fellow to study the role of CRC-SEs in retinal development and diseases such as macular degeneration and diabetic retinopathy. Training in epigenetics, retinal biology and human stem cell research is preferred.   Michael A. Dyer, Ph.D. Investigator, HHMI Chair and Member, Developmental Neurobiology Department Co-leader Developmental Biology and Solid Tumor Program St. Jude Children’s Research Hospital   @MichaelADyerLab www.stjude.org/dyer  
ID
43435
Department
Developmental Neurobiology
Faculty Member
Michael Dyer
A fully funded postdoctoral position is available in the Clements group in the Department of Hematology at St. Jude Children’s Research Hospital to study how the adult hematopoietic system is established during vertebrate embryonic development. We are interested in understanding how early precursors of the sympathetic nervous system and vascular smooth muscle precursors interact with developing endothelial cells to establish the earliest hematopoietic stem cells. Our recent findings (Nature Cell Biology, 19:457-467, 2017) and unpublished data define the existence of this connection in in vertebrates and we are now working to better understand key details. St Jude Children's Research Hospital offers an outstanding research environment, state-of-the-art scientific resources, and a robust community of talented, engaged, and collaborative investigators. We seek an intelligent, friendly, enthusiastic, committed, and capable individual to join our team.   We are particularly seeking an individual with experience in developmental hematopoiesis. In addition to a Ph.D., applicants should have a record of publication, and experience with molecular, biochemical, and cell biological techniques. This position will provide an opportunity for considerable independence and intellectual development, as well as examination of comparative developmental hematopoiesis.   The Clements lab is a friendly group with a keen interest in understanding blood ontogeny and its relationship to malignancy. We support work/life balance and believe that individual happiness is fundamental to scientific discovery and professional fulfillment. Memphis is a vibrant city in the mid-South, with a temperate climate, very active music scene, excellent restaurants, many family-friendly activities, and extremely affordable housing. St Jude Children's Research Hospital offers competitive salary, excellent benefits, and is an equal opportunity employer. Please send a cover letter describing research interests and accomplishments, CV, and the names and addresses of three references to wilson.clements@stjude.org.   https://www.stjude.org/clements https://twitter.com/Zfish_Blood_Lab https://www.linkedin.com/in/wilsonclements/
ID
43118
Department
Hematology
Faculty Member
Wilson Clements
A postdoctoral research associate position is immediately available in the lab of Dr. Jinghui Zhang, Chair of the Department of Computational Biology, for a highly motivated candidate to investigate 3D genome architecture in pediatric cancer. The candidate with be part of the 3D Genome Collaborative Research Consortium formed by distinguished researchers at St. Jude, Dana-Faber Cancer Institute, and MIT. The candidate will be developing innovative methods and perform analysis for discovery of cis-regulatory variants and for investigating heterogeneity in 3D genome architecture at the level of single cell. The appointment will be for 2-5 years, depending on the candidate’s goals, qualifications, and productivity.   Recognized as a world leader of genomic research in pediatric cancer, the Zhang lab has led the characterization of the genomic landscape for over 20 subtypes of pediatric cancers with high-impact publications in Nature, Nature Genetics, Nature Methods, JAMA, Cancer Cell, and NEJM in the last five years. The lab has a well-established track record of developing and publishing novel and high-impact analytical and visualization tools for cancer genomic research. Research in the lab is facilitated by access to the wealth of high-quality data, state-of-art high performance computing facility, robust analytical pipelines, latest laboratory technology and scientific expertise in genomics, cancer biology, and mathematics and computer science.    St. Jude provides a highly interactive and supportive environment for researchers’ career development.   St. Jude Children's Research Hospital is an Equal Opportunity Employer. St. Jude does not discriminate on the basis of race, national origin, sex, genetic information, sexual orientation, gender identity, transgender status, age, religion, disability, veteran's status or disabled veteran's status with respect to employment opportunities. All qualified applicants will be considered for employment. St. Jude engages in affirmative action to increase employment opportunities for minorities, women, veterans and individuals with disabilities.   Interested candidates, please complete online application and submit CV to ComputationalBiologyRecruitment@stjude.org.
ID
43033
Department
Collaborative Research Program
Faculty Member
Jinghui Baker
  Postdoctoral Research Associate-Cell Biology of Neural Development St. Jude Children’s Research Hospital   St. Jude Children’s Research Hospital is a world-renowned institution that is recognized as one of the best places to work in the nation. As a premier center for research and treatment of childhood catastrophic diseases, we employ a diverse team of scientific and healthcare professionals dedicated to the promise of hope. Children from all 50 states and from around the world have come through the doors of St. Jude for treatment, and thousands more have benefited from our research. Description Neuronal polarity is an essential driving force that coordinates the choreography of neural development. How polarity signaling organizes the behavior of immature neurons, in addition to how polarity signaling cascades are regulated are the key topics studied by the Solecki laboratory. These questions are critical to understanding the pathology of neurodevelopmental diseases, where the production of neurons or their subsequent migration is defective.    Exciting postdoctoral positions are available immediately Solecki lab at St. Jude Children’s Research Hospital for talented and highly motivated individuals interested in understanding the cell biology of neuronal polarity or the regulation of nuclear architecture during neuronal differentiation. The Solecki Lab takes a multidisciplinary approach via cutting edge imaging technologies like lattice light sheet (LLS) microscopy or correlative super-resolution electron microscopy (CLEM) and computational approaches to mechanistically analyze the molecular and cellular mechanisms controlling neuronal differentiation, migration, and polarization.   Contact To apply for this position, submit the online application, and send a C.V. and 3 letters of recommendation to: David J. Solecki, PhD, Department of Structural Biology, Mail Stop 311, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA, david.solecki@stjude.org.
ID
42727
Department
Developmental Neurobiology
Faculty Member
David Solecki

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