Postdoctoral Training Opportunities

Cures don't just happen. St. Jude Children's Research Hospital is committed to the education and training of the next generation of research scientists. St. Jude trainees are able to learn from clinical and basic science investigators who work in close proximity and interact regularly to translate scientific discoveries into improved therapies for children.


If you are a highly motivated individual who wants to work at a world-class institution with state of the art facilities and learn from investigators at the forefront of their fields, consider advancing your research training at St. Jude.

Here are our postdoctoral research training opportunities. Please click on the position title for more information, and apply from that page if you are interested.

 

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A bioinformatics postdoctoral position is available in the Savic laboratory to study the pharmacogenomics of treatment in childhood leukemia. The primary research focus of the Savic laboratory involves studying the gene regulatory architecture of pediatric leukemia to define how the noncoding portion of the human genome impacts chemotherapeutic drug response, chemotherapeutic drug resistance and leukemia relapse. To address these critical questions, the Savic laboratory applies various orthogonal functional genomic assays and high-throughput screening approaches to identify and functionally characterize genetically and/or epigenetically disrupted cis-regulatory elements impacting childhood leukemia pharmacogenomics. The long-term goal of the Savic laboratory is to gain a better understanding of the genetic and epigenetic underpinnings of chemotherapeutic drug resistance and relapse in childhood leukemia.
ID
46338
Department
Pharmaceutical Sciences
Faculty Member
Daniel Savic
A postdoctoral position is available in the Savic laboratory to study the pharmacogenomics of treatment in childhood leukemia. The primary research focus of the Savic laboratory involves studying the gene regulatory architecture of pediatric leukemia to define how the noncoding portion of the human genome impacts chemotherapeutic drug response, chemotherapeutic drug resistance and leukemia relapse. To address these critical questions, the Savic laboratory applies various orthogonal functional genomic assays and high-throughput screening approaches to identify and functionally characterize genetically and/or epigenetically disrupted cis-regulatory elements impacting childhood leukemia pharmacogenomics. The long-term goal of the Savic laboratory is to gain a better understanding of the genetic and epigenetic underpinnings of chemotherapeutic drug resistance and relapse in childhood leukemia.
ID
46372
Department
Pharmaceutical Sciences
Faculty Member
Daniel Savic
We are seeking candidates with Ph.D. in chemistry or life sciences, or similar fields for Postdoctoral position in the Metabolic Imaging group led by Dr. Puneet Bagga. The ideal candidate will have strong background and interest in cellular metabolism and patient-derived xenograft models. You will join a highly collaborative group focused on developing and applying magnetic resonance imaging and spectroscopic methods for clinical translation at the Department of Diagnostic Imaging. Experience in MRI/MRS/NMR/LC-MS, and in performing small animal and/or human subject imaging is a plus. The candidate will have demonstrated analytical and communication skills, including the ability to effectively describe scientific material to both specialized and lay audiences, and strong CV, having published in reputable journals and presented at international meetings.   Individuals interested in applying should submit: - Current CV - A cover letter including candidate’s reasons for pursuing research in this field - Name and contact information of 3 referees
ID
46342
Department
Diagnostic Imaging
Faculty Member
Puneet Bagga
A postdoctoral researcher position is available in Dr. Yong Feng’s laboratory at the Department of Immunology in St. Jude Children’s Research Hospital.  Research in Dr. Feng’s laboratory is utilizing innovative approaches and cutting-edge technologies to decipher the mechanisms governing T cell immune tolerance.   Besides the unmatched benefit for postdoctoral fellows at St. Jude Children’s Research Hospital, the extraordinary internal support and state-of-the-art facilities provide an exceptional environment to train the next generation of biomedical investigators.  In addition to applying, a cover letter of interest, CV and three recommendation letters should be sent to Yong.Feng@STJUDE.ORG
ID
46351
Department
Immunology
Faculty Member
Yongqiang Feng
Dr. Zhaoming Wang, a joint faculty member between St. Jude Department of Epidemiology and Cancer Control and the Department of Computational Biology, is seeking highly motivated and creative candidates for a fully supported postdoctoral fellow position to conduct high impact clinical research primarily in genetic epidemiology of cancers (childhood and subsequent adulthood cancers), biomarker discovery for treatment- and/or aging-related late effects of survivors of childhood cancer, and omics-based precision preventive medicine.   You will have the opportunity to work with large-scale whole-genome sequencing, whole-exome sequencing, epigenetic profile, and RNA sequencing data for a well-established cohort of childhood cancer survivors with clinically assessed rich set of phenotypes including subsequent neoplasms.   In this position, you will gain extensive experience and training in genetic and molecular epidemiology, as well as programming skills and analytic expertise in computational biology. You will be provided with opportunities to work within a multi-disciplinary research environment and interact with leaders in the fields of pediatric cancer, genetics, epigenetics, functional genomics, and survivorship research. The training position is supported by a V-Foundation grant for conducting social epigenomics studies in adult survivors of childhood cancer.
ID
46329
Department
Epidemiology & Cancer Control
Faculty Member
Zhaoming Wang
We seek a highly motivated postdoctoral research associate to join the group of Dr. Mario Halic in the Department of Structural Biology at St. Jude Children's Research Hospital.   The Halic lab studies the epigenetic regulation of gene expression using genetics, molecular biology, biochemistry and structural biology approaches. In particular, we study heterochromatin formation and the chromatin-modifying proteins involved in this process. We use cryo-EM methodologies to examine processes involved in chromatin organization and also apply genetics and molecular biology approaches to investigate heterochromatin formation in fission yeast. More information about the lab, publications and ongoing projects can be found here: https://www.stjude.org/research/labs/halic-lab.html   This is an excellent opportunity for an early-career scientist to broaden their skill set. You will join a vibrant community at the Department of Structural Biology at St. Jude Children's Research Hospital, with access to state-of-the-art facilities that enable integrative structural biology and biophysics investigations, including cryo-EM, X-ray crystallography and NMR, single-molecule imaging, protein-protein interactions, combined with computational and data-science approaches. More information about the department can be found here: https://www.stjude.org/research/departments/structural-biology.html   St. Jude Children’s Research Hospital has a highly collaborative research environment, with numerous institutional shared resources and core facilities. In addition, postdocs benefit from excellent salary and benefits package: https://www.stjude.org/education-training/advanced-training/postdoctoral-fellows/funding-benefits-for-postdocs.html   Applicants should submit CV and cover letter (describing research experience and interests) and names and addresses for 3 references.
ID
46108
Department
Structural Biology
Faculty Member
Mario Halic
We seek a highly motivated postdoctoral research associate to join the group of Dr. Mario Halic in the Department of Structural Biology at St. Jude Children's Research Hospital. The Halic lab studies the epigenetic regulation of gene expression using genetics, molecular biology, biochemistry and structural biology approaches. In particular, we study heterochromatin formation and the chromatin-modifying proteins involved in this process. We use cryo-EM methodologies to examine processes involved in chromatin organization and also apply genetics and molecular biology approaches to investigate heterochromatin formation in fission yeast. More information about the lab, publications and ongoing projects can be found here: https://www.stjude.org/research/labs/halic-lab.html This is an excellent opportunity for an early-career scientist to broaden their skill set. You will join a vibrant community at the Department of Structural Biology at St. Jude Children's Research Hospital, with access to state-of-the-art facilities that enable integrative structural biology and biophysics investigations, including cryo-EM, X-ray crystallography and NMR, single-molecule imaging, protein-protein interactions, combined with computational and data-science approaches. More information about the department can be found here: https://www.stjude.org/research/departments/structural-biology.html St. Jude Children’s Research Hospital has a highly collaborative research environment, with numerous institutional shared resources and core facilities. In addition, postdocs benefit from excellent salary and benefits package: https://www.stjude.org/education-training/advanced-training/postdoctoral-fellows/funding-benefits-for-postdocs.html   Applicants should submit CV and cover letter (describing research experience and interests) and names and addresses for 3 references.
ID
45062
Department
Structural Biology
Faculty Member
Mario Halic
Madan Babu's Group at the Center of Excellence for Data-Driven Discovery and the Department of Structural Biologyis seeking a highly driven, full-time Network Biologist and Multiomics Researcher. This post will be part of a newly established Centre for Adipocyte Signaling (ADIPOSIGN) funded by a major grant from the Novo Nordisk Foundation. This position is available immediately with four years of funding. ADIPOSIGN is run by four partners with highly complementary expertise in the fields of adipocyte biology, transcriptional regulation, signal transduction, physiology, and computational systems biology:   Susanne Mandrup, Prof., Dept. Biochemistry and Molecular Biology, SDU, DK Jan-Wilhelm Kornfeld, Prof., Dept. Biochemistry and Molecular Biology, SDU, DK Madan Babu, Member, Dept. of Structural Biology SJCRH, USA Zach Gerhart-Hines, Assoc. Prof., NNF Center for Basic Metabolic Research, University of Copenhagen, DK   The ideal candidate will be able to identify, develop, and use computational biology methods to mine, integrate, visualize, and analyze multiple large-scale omics datasets and biomolecular network data (transcriptional, metabolic, signaling networks) for hypothesis generation and creation of network models of obesity. You will establish computational pipelines to organize and interrogate multiple omics datasets as well as develop and maintain an internal data resource for the consortium.  When submitting your application, please include your CVand a cover letter.    This position requires relocation to Memphis, TN. When possible, it will involve travel for collaborative purposes to Denmark. You will be working in a highly dynamic and collaborative environment, and will be expected to communicate complex informatics principles, methods, analyses and results to scientists from diverse backgrounds in the consortium. Excellent interpersonal and communication skills are a must, as you will interact directly with both Computational Biologists and Experimentalists in a highly interdisciplinary environment.   Ranked #1 in the U.S. in Pediatric Cancer, St. Jude Children's Research Hospital is a NCI-designated Comprehensive Cancer Center, and home to the Pediatric Cancer Genome Project. The St. Jude campus is a truly unique research environment, encompassing state-of-the-art HPC facilities, world-leading oncology basic research, outstanding Shared Resources and Core Facilities and a dedicated translational Chemical Biology and Therapeutics department. The $412M Advanced Research Center, opened in 2021, doubles the campus’ research space and adds support for an additional 1000 employees. There is a vibrant Data Science community at St. Jude, with opportunities to interact with researchers in the Biostatistics and Computational Biology Departments, and tremendous support from the Center for Applied Bioinformatics. The St. Jude Postdoctoral Association provides tremendous support for professional and career development.   St. Jude Children’s Research Hospital is consistently named as one of Fortune magazine and Glassdoor.com’s “Best Places to Work,” as well as “Best Workplace for Women” and “Best Workplace for Diversity.” We are in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food, and culture. Mild winters and beautiful green outdoor spaces are part of the reasons why Forbes recently named Memphis the 4th happiest city in which to work. Cost of living and high quality of life are other attractions; Money magazine listed Memphis as one of the least expensive cities in which to raise a child. St. Jude facilities and salaries are highly competitive. The Babu Group strives to build and maintain a culture of respect, diversity, and inclusion and we strongly feel these values directly contribute to the dynamic and intellectually stimulating scientific environment we can provide.   Preferred Qualifications include: - Extensive experience in working with omics datasets and biomolecular networks (e.g. high-throughput transcriptomics or epigenomics data sets, protein-protein interaction networks, PTMs, signaling pathways, and gene regulatory networks) - Experience with developing web interfaces for data analysis, visualization and dissemination (e.g., R Shiny) - Experience with developing and maintaining databases (ideally including graph databases) - Experience with representing complex datasets and networks as interpretable figures and novel data visualisation methods - Experience with diverse statistical data analysis approaches is desirable (Bayesian and non-Bayesian statistical methods) - Expertise in adipocyte biology or other fields relevant to the study of obesity is desirable - Interest and expertise in GPCR signaling, transcription, metabolic pathways and/or nuclear receptors is desirable - Understanding of human genetics, polygenic risk scores, genome-wide association studies and analysis methods
ID
45019
Department
Structural Biology
Faculty Member
Madan Babu Mohan
Postdoctoral Researcher in HPV Cancer Prevention   APPLY here for the Postdoctoral Researcher.   St. Jude Children's Research Hospital is leading the way the world understands, treats, and defeats childhood cancer and other childhood diseases. Our mission, to advancecures, and means for prevention, for pediatric catastrophic diseases through research and treatment, is at the center of our work and everything we do. We are a great place to work, consistently ranked among Fortune Magazine’s 100 Best Places to Work For®. At St. Jude, employees are encouraged to contribute new ideas, no matter who you are or what you do, to make the organization the best it can be.   We are seeking two outstanding candidates for postdoctoral fellowship positions in the HPV Cancer Prevention Program at St. Jude Children’s Research Hospital. The postdoctoral positions offer an intensive, mentored training experience in implementation science, community-engaged research, health equity, and cancer prevention through HPV vaccination. Postdoctoral fellows will be encouraged to support the research foci of the HPV Cancer Prevention Program and develop their own research programs in implementation science with a specific focus on HPV vaccination or other related topics (e.g., health equity, partner and engaged research approaches, building vaccine confidence, supporting vaccinations in clinical and community settings, public policy and advocation, communications, etc.) using implementation science frameworks.   To apply or learn more, please contact: Heather M. Brandt, PhD Director, HPV Cancer Prevention Program Member, Department of Epidemiology and Cancer Control Department of Epidemiology and Cancer Control St. Jude Children’s Research Hospital Heather.Brandt@stjude.org   Learn more about the HPV Cancer Prevention Program at stjude.org/hpv.  
ID
44854
Department
HPV Cancer Prevention
Faculty Member
Heather Brandt
St. Jude Children's Research Hospital is leading the way the world understands, treats, and defeats childhood cancer and other childhood diseases. Our mission, to advancecures, and means for prevention, for pediatric catastrophic diseases through research and treatment, is at the center of our work and everything we do. We are a great place to work, consistently ranked among Fortune Magazine’s 100 Best Places to Work For®. At St. Jude, employees are encouraged to contribute new ideas, no matter who you are or what you do, to make the organization the best it can be.   We are seeking two outstanding candidates for postdoctoral fellowship positions in the HPV Cancer Prevention Program at St. Jude Children’s Research Hospital. The postdoctoral positions offer an intensive, mentored training experience in implementation science, community-engaged research, health equity, and cancer prevention through HPV vaccination. Postdoctoral fellows will be encouraged to support the research foci of the HPV Cancer Prevention Program and develop their own research programs in implementation science with a specific focus on HPV vaccination or other related topics (e.g., health equity, partner and engaged research approaches, building vaccine confidence, supporting vaccinations in clinical and community settings, public policy and advocation, communications, etc.) using implementation science frameworks.   To apply or learn more, please contact: Heather M. Brandt, PhD Director, HPV Cancer Prevention Program Member, Department of Epidemiology and Cancer Control Department of Epidemiology and Cancer Control St. Jude Children’s Research Hospital Heather.Brandt@stjude.org   Learn more about the HPV Cancer Prevention Program 
ID
44855
Department
HPV Cancer Prevention
Faculty Member
Heather Brandt
St. Jude is seeking outstanding candidates for postdoctoral fellowship positions in infectious disease therapeutics. This NIH sponsored training program has been designed to leverage the outstanding research infrastructure at St. Jude to train top-tier postdoctoral fellows with the necessary skills to lead independent research programs in the discovery of infectious diseases therapeutics including small molecule and vaccine candidates.   Postdoctoral preceptors associated with the program are drawn from the departments of Infectious Diseases, Structural Biology, Chemical Biology & Therapeutics, Immunology and Pharmaceutical Sciences, bringing complementary expertise to this enterprise that not only seeks to understand the biology of infection but also strives to develop therapies to combat them. This expertise includes structural biology, virology and bacteriology, microbial genomics, drug discovery, high-throughput screening, medicinal chemistry, immune responses to infection and therapies, and vaccine platforms and adjuvants. All trainees will be instructed in grant writing, rigor and reproducibility, ethics and mentoring. Short-term internships in pharmaceutical companies or visits to international clinical sites in conjunction with the SJCRH Global Program are integral parts of the curriculum. Collaborations between the preceptors is encouraged to provide a cross-disciplinary approach to the training program. St. Jude offers highly competitive stipends and benefits and fosters professional development.
ID
44989
Department
Academic Programs
Faculty Member
Stephen White
Overview   Outstanding candidates are invited to apply for a medical physics postdoctoral research associate in  the Department of Radiation Oncology at St. Jude Children’s Research Hospital. In this two-year position, you will benefit from world-class resources and exceptional training in a top-ranked research environment while helping to advance treatment options for children with cancer.   Research Focus   The primary focus of this postdoctoral research associate position is on using Big Data analytics tools to improve treatment plan quality in proton therapy. We are especially interested in understanding the roles of linear energy transfer and treatment plan robustness. Research aims include the following:   - Contributing to data infrastructure efforts by reviewing clinical treatment plans, analyzing Monte Carlo dose distributions, and using good data practices   - Testing and validating novel analytics tools on curated data sets to better understand radiation therapy outcomes of children with cancer   - Investigating ways in which artificial intelligence may contribute to improving outcomes models   St. Jude offers a collaborative research environment and exceptional support for scientific discovery. The successful candidate will work closely with the principal investigators, computational scientists, and students in the research group. The postdoctoral research associate will interact with radiation oncologists, information technology support staff, clinical therapy and physics staff, and clinical scientists. Research activities will include data collection, image analysis, dosimetry comparisons with treatment planning systems and Monte Carlo calculations, experimental validation with proton beams, and report and manuscript preparation. Opportunities to gain clinical experience in proton and photon radiotherapy physics may be made available pending adequate research progress.   Resources and Equipment   As part of the Department of Radiation Oncology, the postdoctoral research associate will have access to world-class resources, including the world’s first proton therapy center with pencil-beam scanning technology that is designated solely for treating pediatric cancer, a detector-based spectral CT scanner that was the first in the world to be installed in a radiation oncology department, state-of-the-art 1.5T and 3T MR scanners, and a recently installed digital PET/CT scanner. The department also has a full suite of radiation oncology software, including Eclipse, RayStation, and Pinnacle treatment planning systems and MiM Maestro.   Contact Information   Austin M. Faught, PhD, DABR Assistant Member, Department of Radiation Oncology 262 Danny Thomas Place Memphis, TN 38105 E-mail: austin.faught@stjude.org | Web: www.stjude.org/faught
ID
44951
Department
Radiation Oncology
Faculty Member
Austin Faught
POSTDOCTORAL POSITION to study the function of novel CAR T cell-based therapies for pediatric brain tumors   St. Jude Children's Research Hospital, Memphis, Tennessee, USA We are seeking a highly motivated and ambitious postdoctoral fellow to join the group of Dr. Giedre Krenciute. The lab is located in the Department of Bone Marrow Transplantation and Cellular Therapy at St. Jude Children’s Research Hospital in Memphis, TN. Our lab is working on highly translational immunology research, with the focus on brain tumors. We use genetically engineered human or murine T cells to design novel, long-lasting and safe therapeutic approaches for pediatric brain tumors.   Major projects include: - Designing, generating, and optimizing chimeric antigen receptors (CARs) specific for pediatric brain tumors. - Enhancing CAR T cell effector function and longevity using different genetic manipulations - Studying brain tumor microenvironment and its effect on CAR T cell function   For representative publications, please see: Haydar D, Houke H, Chiang J, Yi Z, Odé Z, Caldwell K, Zhu X, Mercer KS, Stripay JL, Shaw TI, Vogel P, DeRenzo C, Baker SJ, Roussel MF, Gottschalk S, KrenciuteG. Cell surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery. Neuro Oncol. 2020 Prinzing B, Schreiner P, Bell M, Fan Y, Krenciute G*, Gottschalk S*. MyD88/CD40 signaling retains CAR T cells in a less differentiated state. JCI Insight. 2020. *co-senior authors Odé Z, Condori J, Peterson N, Zhou S, Krenciute G. CRISPR-Mediated Non-Viral Site-Specific Gene Integration and Expression in T Cells: Protocol and Application for T-Cell Therapy. Cancers (Basel). 2020 Yi Z, Brooke LP, Cao F, Gottschalk S, Krenciute G. Optimizing EphA2-CAR T cells for the Adoptive Immunotherapy of Glioma. Molecular Therapy - Methods & Clinical Development. 2018 Krenciute G, Prinzing BL, Yi Z, Wu MF, Liu H, Dotti G, Balyasnikova IV, Gottschalk S. Transgenic expression of IL15 improves antiglioma activity of IL13Ralpha2-CAR T cells but results in antigen-loss variants. Cancer Immunol Res. 2017   Interested applicants should send their CV, a cover letter describing research experience and interests, and names and email addresses of three references to: giedre.krenciute@stjude.org
ID
44927
Department
Bone Marrow Trans & Cell Thrpy
Faculty Member
Giedre Krenciute
POSTDOCTORAL POSITION to study the function of novel CAR T cell-based therapies for pediatric brain tumors   St. Jude Children's Research Hospital, Memphis, Tennessee, USA We are seeking a highly motivated and ambitious postdoctoral fellow to join the group of Dr. Giedre Krenciute. The lab is located in the Department of Bone Marrow Transplantation and Cellular Therapy at St. Jude Children’s Research Hospital in Memphis, TN. Our lab is working on highly translational immunology research, with the focus on brain tumors. We use genetically engineered human or murine T cells to design novel, long-lasting and safe therapeutic approaches for pediatric brain tumors.   Major projects include: - Designing, generating, and optimizing chimeric antigen receptors (CARs) specific for pediatric brain tumors. - Enhancing CAR T cell effector function and longevity using different genetic manipulations - Studying brain tumor microenvironment and its effect on CAR T cell function   For representative publications, please see: Haydar D, Houke H, Chiang J, Yi Z, Odé Z, Caldwell K, Zhu X, Mercer KS, Stripay JL, Shaw TI, Vogel P, DeRenzo C, Baker SJ, Roussel MF, Gottschalk S, KrenciuteG. Cell surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery. Neuro Oncol. 2020 Prinzing B, Schreiner P, Bell M, Fan Y, Krenciute G*, Gottschalk S*. MyD88/CD40 signaling retains CAR T cells in a less differentiated state. JCI Insight. 2020. *co-senior authors Odé Z, Condori J, Peterson N, Zhou S, Krenciute G. CRISPR-Mediated Non-Viral Site-Specific Gene Integration and Expression in T Cells: Protocol and Application for T-Cell Therapy. Cancers (Basel). 2020 Yi Z, Brooke LP, Cao F, Gottschalk S, Krenciute G. Optimizing EphA2-CAR T cells for the Adoptive Immunotherapy of Glioma. Molecular Therapy - Methods & Clinical Development. 2018 Krenciute G, Prinzing BL, Yi Z, Wu MF, Liu H, Dotti G, Balyasnikova IV, Gottschalk S. Transgenic expression of IL15 improves antiglioma activity of IL13Ralpha2-CAR T cells but results in antigen-loss variants. Cancer Immunol Res. 2017   Interested applicants should send their CV, a cover letter describing research experience and interests, and names and email addresses of three references to: giedre.krenciute@stjude.org
ID
44929
Department
Bone Marrow Trans & Cell Therapy
Faculty Member
Giedre Krenciute
The Zhou lab in the department of Computational Biology is seeking a postdoctoral trainee who’s passionate about promoting biomedical and cancer research and addressing big data challenges from the unique perspective of scientific data visualization. Dr. Zhou leads a team of bioinformatics scientists and web developers to investigate and implement cutting edge methodologies to utilize multi-omics data in cancer and population science.   The initial appointment will be for 1-2 years and can be renewed for up to a total of 5 years, depending on the candidate’s goals and qualifications.   Interested candidates, please complete the online application and email your CV and cover letter to xin.zhou@stjude.org. Please include areas of specific interest in a brief cover letter.
ID
44920
Department
Computational Biology
Faculty Member
Xin Zhou
A postdoctoral fellowship position is available for a highly motivated individual interested in the neural circuit mechanisms of schizophrenia. Our laboratory conducts 2-photon laser-scanning microscopy imaging of neuronal activity in awake mice, with a focus on mouse models of 22q11.2 deletion syndrome and 15q11 duplication syndrome, high-risk factors for developing psychiatric disorders, especially schizophrenia and autism, respectively. Preference will be given to applicants who have received their Ph.D. degrees in neuroscience or engineering within the last 3 years and have experience in computational neuroscience and data mining using machine learning methods.   In vivo imaging in awake mice and rats will be performed on 3 dedicated 2-photon microscopes. The fellow will work with a dedicated team of computer scientists. The laboratory also is equipped to perform single-cell electrophysiology, two-photon imaging, and two-photon glutamate uncaging in brain slices.   The fellow will benefit from both an outstanding work environment in the laboratory and a highly collaborative St. Jude community. The successful candidate will join a diverse team of researchers whose efforts are directed toward understanding behavior at the levels of neural circuits, individual neurons, synapses, and molecules. The laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including an integrated support structure for rodent behavior testing, 3-dimensional brain organoids, in vivo and ex vivo cellular imaging, bioinformatics, production of genetically engineered animal models, single-cell profiling, and advanced image processing and analysis. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies.         St. Jude Children’s Research Hospital offers an excellent salary and benefits package and is an equal opportunity employer. Interested applicants should send their CVs and the names and addresses of 3 references to: Stanislav Zakharenko, M.D., Ph.D. Department of Developmental Neurobiology, MS 322 St. Jude Children’s Research Hospital 262 Danny Thomas Place Memphis, TN 38105 stanislav.zakharenko@stjude.org
ID
44826
Department
Developmental Neurobiology
Faculty Member
Stanislav Zakharenko
Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital. As a fellow you will join our faculty in the Department of Biostatistics in providing statistical support and developing innovative statistical methods for research projects at the cutting edge of biomedical research.    The department is seeking an outstanding postdoctoral fellow to engage in the development of statistical methodology and software for complex biomedical data such as longitudinal, imaging, wearable device, and genetic/genome studies with broad application in pediatric cancer and mental health.     For eight consecutive years, St. Jude has ranked among the top places to work in the U.S. by Forbes Magazine. Salary and benefits are competitive. Apply online and send cover letter, CV, and three recommendation letters to Dr. Tomi Mori via e-mail at tomi.mori@stjude.org.    Appointment is for two years. 
ID
44718
Department
Biostatistics
Faculty Member
Motomi Mori
Postdoctoral Research Associate in Neuroscience / Neurobiology   The Bikoff lab (https://www.bikofflab.org/) is seeking a highly motivated postdoctoral researcher interested in using quantitative approaches to behavior, in vivo calcium imaging, and optogenetics/chemogenetics to study neural circuitry in mice.   We aim to understand the functional organization of neural circuits that control movement, including how descending pathways from the brain interact with spinal circuits to implement motor output. The lab approaches this problem from multiple perspectives, using mouse genetics, single-cell transcriptomics, viral tracing and whole-brain imaging, and animal behavior to explore the role of molecularly discrete subsets of neurons in motor control. We welcome applicants from diverse backgrounds that would thrive in a highly collaborative, interactive, and supportive environment that provides the freedom to independently develop a research project.   The Bikoff lab is strongly committed to providing individual mentoring and training for all lab members, as well as additional support for career development.   Applications: Individuals with evidence of scientific accomplishment are encouraged to apply by sending their CV, a brief description of research interests, and contact information for three references to: jay.bikoff@stjude.org.
ID
44720
Department
Developmental Neurobiology
Faculty Member
Jay Bikoff
We are looking for Post-doctoral Research Associate candidates to study protein kinases. The candidate will join an inter-disciplinary Blue Sky initiative on “Seeing the Invisible in Protein Kinases”, which is supported by $35M in institutional funding by St. Jude Children's Research Hospital. The project will extend the ultra-high field NMR spectroscopy and biochemistry approaches developed recently by the Kalodimos lab (Science 2020, 370, eabc2754) to study the human kinome. This is a large-scale project that aims to detect and structurally characterize the distinct conformational states populated by kinases, and to dissect the mechanisms of allosteric regulation and those underpinning oncogenic and drug-resistance mutations. The unparalleled NMR center at St. Jude includes three 600 MHz, two 700 MHz, four 800 MHz, 850 MHz, and the first 1.1 GHz. We expect this initiative to have a profound impact on the field, transforming our understanding of protein kinases.  St. Jude Children’s Research Hospital offers a remarkable opportunity to perform cutting edge research with outstanding institutional support and exceptional shared core facilities in an environment of open collaboration, educational advancement, and training opportunities. St. Jude is consistently ranked on Fortune Magazine’s and Glassdoor’s “100 Best Places to Work” for companies with 1,000 or more employees. We are located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food, and culture. Mild winters and beautiful green outdoor spaces are part of the reasons why Forbes recently named Memphis the 4th happiest city in which to work. Cost of living and high quality of life are other attractions; Money magazine listed Memphis as one of the least expensive cities in which to raise a child. St. Jude facilities and salaries are highly competitive.
ID
44684
Department
Structural Biology
Faculty Member
Charalampos Kalodimos
We are looking for Post-doctoral Research Associate candidates to study protein kinases. The candidate will join an inter-disciplinary Blue Sky Initiative on “Seeing the Invisible in Protein Kinases”, which is supported by $35M in institutional funding by St. Jude Children's Research Hospital. The project will extend the ultra-high field NMR spectroscopy and biochemistry approaches developed recently by the Kalodimos lab (Science 2020, 370, eabc2754) to study the human kinome. This is a large-scale project that aims to detect and structurally characterize the distinct conformational states populated by kinases, and to dissect the mechanisms of allosteric regulation and those underpinning oncogenic and drug-resistance mutations. The unparalleled NMR center at St. Jude includes three 600 MHz, two 700 MHz, four 800 MHz, 850 MHz, and the first 1.1 GHz. We expect this initiative to have a profound impact on the field, transforming our understanding of protein kinases.  St. Jude Children’s Research Hospital offers a remarkable opportunity to perform cutting edge research with outstanding institutional support and exceptional shared core facilities in an environment of open collaboration, educational advancement, and training opportunities. St. Jude is consistently ranked on Fortune Magazine’s and Glassdoor’s “100 Best Places to Work” for companies with 1,000 or more employees. We are located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food, and culture. Mild winters and beautiful green outdoor spaces are part of the reasons why Forbes recently named Memphis the 4th happiest city in which to work. Cost of living and high quality of life are other attractions; Money magazine listed Memphis as one of the least expensive cities in which to raise a child. St. Jude facilities and salaries are highly competitive.
ID
44685
Department
Structural Biology
Faculty Member
Charalampos Kalodimos

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