Postdoctoral Research Associate - Chemical Biology & Therapeutics

Job Location US-TN-Memphis
Chemical Biology & Therapeutic
Faculty Member
Tommaso Cupido


The Cupido lab at St Jude Children Research Hospital (Memphis, TN) is seeking postdoctoral fellows who wish to conduct structural and chemical biology research and gain experience as independent researchers. These positions are core funded and the expected start date will be in January 2022 but can be flexible.

About The Lab
The Cupido Lab opened on January 2021 in the Department of Chemical Biology & Therapeutics, and is well equipped for biochemistry and chemical biology research. The Lab has also full access to unparalleled resources and expertise in an open environment at St Jude. Our research focuses on discovering drug-like chemical modulators for protein machines and for the analysis of molecular mechanisms that regulate the flow of genetic information (e.g. gene transcription and splicing). Our efforts are highly multidisciplinary, and combine small molecule chemistry with structural and genomic approaches. One major focus is to understand the mechanism and regulation of nucleic acid-interacting enzymes whose aberrant function is implicated in cancer development. We seek to control the dynamics of these protein machines, using chemicals we design, to identify and then test novel pharmacological approaches for treating cancer.

To apply, please send a cover letter emphasizing research background and career goals, and a CV.

Minimum Experience

Candidates should have expertise on biochemistry and structural biology. Programming and/or bioinformatic experience in data analysis is preferred. Successful applicants are expected to lead projects and gain multidisciplinary training in cutting edge structural and molecular technologies. This is a great opportunity for enthusiastic and highly motivated postdocs, who will be encouraged to take advantage of the outstanding scientific technology platforms at St Jude (including state-of-the-art centers for Cryo-EM, X-Ray crystallography, biomolecular NMR, and high-throughput chemical and genomic screenings, among others) and integrate different experimental approaches to the research project.

Other Information

COVID-19 vaccine:

As of September 10, 2021, St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.

St. Jude is an Equal Opportunity Employer

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