Postdoctoral Research Associate

Job Location US-TN-Memphis
ID
43583
Department
Structural Biology
Faculty Member
Tanja Mittag

Summary

The Mittag laboratory invites applications for a Postdoctoral Research Fellow to work on an interdisciplinary project that will involve in vitro biophysics studies of phase separation and cell biological approaches to assess function. The latter component is in collaboration with Linda Hendershot’s laboratory in the Department of Tumor Cell Biology. The project seeks to delineate the molecular mechanisms by which cancer mutations in the tumor suppressor SPOP, a ubiquitin ligase subunit, result in dysregulation of substrates. An important goal is to assess the role of phase separation for SPOP function.

 

The successful candidate will join a highly collaborative laboratory focused on elucidating mechanisms and function of biomolecular condensates in the Department of Structural Biology, with access to state-of-the-art instrumentation and expertise in NMR spectroscopy, X-ray crystallography, cryo-EM, single molecule techniques, and protein technology. St. Jude Children’s Research Hospital is a Fortune 100 Best Company that offers competitive salary and benefits.  

 

 

Contact Information 

Tanja Mittag, PhD 

Department of Structural Biology 

St. Jude Children’s Research Hospital 

262 Danny Thomas Place 

Memphis, TN  38105-3678 

E-mail: tanja.mittag@stjude.org 

https://www.stjude.org/mittag 

 

Responsibilities

The successful candidate will take a leadership role in connecting ongoing research projects related to SPOP biology and biophysics. The candidate will receive training in biophysics and cell biological approaches, and support with career development. 

Minimum Education

Given that the project will involve interdisciplinary research at the interface of biophysics and cell biology, the successful candidate should have a Ph.D. in in vitro structural biology/biophysics or cell biology. They will add to their experimental repertoire through tight integration in the Mittag and Hendershot labs. The candidate should demonstrate an academic record of excellence, and a strong interest in the growing field of biomolecular condensates.

EEO

St. Jude is an Equal Opportunity Employer

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