Postdoctoral Research Associate

Job Location US-TN-Memphis
ID
42968
Department
Chemical Biology & Therapeutic
Faculty Member
Anang Shelat

Summary

A postdoctoral position is available immediately in the laboratories of Dr. Anang Shelat and Dr. Phil Potter within the Department of Chemical Biology and Therapeutics to assess the therapeutic potential of selective transcriptional perturbation in pediatric cancers using small molecules. The identification of the mechanism of action of these compounds, and the molecular determinants which govern susceptibility and resistance, are key motivations for this position. This work will directly support the institution’s translational program, with the goal of identifying clinically relevant chemotherapeutic strategies for pediatric cancer.

 

The applicant must have a strong background in genomics, epigenetics, biochemistry, and molecular biology. The applicant must be comfortable with developing, validating, and executing biochemical and cell-based assays to quantify transcription and transcriptional complexes. The applicant will be expected to apply high-throughput screening technologies to identify novel small-molecules or drug combination strategies. The applicant is expected to work alongside cancer biologists, computational biologists, pharmacologists, and clinicians in a project team environment, with the end goal of contributing to the discovery of small molecules with the potential to treat pediatric cancers. 

Minimum Education

The applicant must have a strong background in genomics, epigenetics, biochemistry, and molecular biology. The applicant must be comfortable with developing, validating, and executing biochemical and cell-based assays to quantify transcription and transcriptional complexes. The applicant will be expected to apply high-throughput screening technologies to identify novel small-molecules or drug combination strategies. The applicant is expected to work alongside cancer biologists, computational biologists, pharmacologists, and clinicians in a project team environment, with the end goal of contributing to the discovery of small molecules with the potential to treat pediatric cancers. 

Required Credentials

Highly motivated individuals with a recent PhD degree and evidence of scientific accomplishment are encouraged to apply. Good communication skills and willingness to work in a team environment are essential. A background in modern drug discovery techniques, chemistry, and chemical biology is desirable. 

EEO

St. Jude is an Equal Opportunity Employer

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