• Postdoctoral Research Associate

    Job Location US-TN-Memphis
    Faculty Member
    Charles Roberts
  • Summary

    A postdoctoral fellowship is available in the laboratory of Dr. Charles Roberts in the Department of Oncology. Dr. Roberts’ lab studies the epigenetic regulation of gene expression. In particular we are studying chromatin-modifying proteins with a major focus on the SWI/SNF (BAF) chromatin remodeling/tumor suppressor complex and its relationship to cancers. Recent studies have revealed that genes encoding subunits of the SWI/SNF complex are mutated in over 20% of all cancers, a rate approaching that of p53, making this the most frequently mutated chromatin regulator in human malignancies. Research in the Roberts laboratory is designed to discover the mechanism by which SWI/SNF complex contributes to the regulation of gene expression and lineage specification, and the mechanisms by which mutation of the tumor suppressor subunits drives cancer formation.  We also seek to identify specific vulnerabilities that are conferred by SWI/SNF mutation with the goal of identifying novel therapeutic opportunities. We seek an ambitious postdoctoral scientist with a strong background in molecular biology, cell biology, cancer biology, and/or genetics/epigenetics of tumorigenesis. Currently there are several projects ongoing in the laboratory involving the use of a variety of model systems that have been engineered in the lab including mouse models, primary cells, and cell lines as well as the use of large sequencing, CRISPR, and drug vulnerability data sets

    Minimum Education

    Candidates should have recently earned/expect to earn a Ph.D. and have published in peer-reviewed journals. A prerequisite is experience in basic methods of molecular biology and biochemistry.


    St. Jude is an Equal Opportunity Employer

    No Search Firms:

    St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.


    Sorry the Share function is not working properly at this moment. Please refresh the page and try again later.
    Share on your newsfeed

    Stay connected

    Not ready to apply? Become a St. Jude Career Insider to stay up-to-date on our opportunities.