Neuronal polarity is an essential driving force that coordinates the choreography of neural development. How polarity signaling organizes the behavior of immature neurons, in addition to how polarity signaling cascades are regulated are the key topics studied by the Solecki laboratory. These questions are critical to understand the pathology of neurodevelopmental diseases, where the production of neurons or their subsequent migration is defective.
Exciting postdoctoral positions are available immediately in the Solecki lab at St. Jude Children’s Research Hospital for talented and highly motivated individuals interested in understanding the cell biology of neuronal polarity or the regulation of nuclear architecture during neuronal differentiation. The Solecki Lab takes a multidisciplinary approach via cutting edge imaging technologies like lattice light sheet (LLS) microscopy or correlative super-resolution electron microscopy (CLEM) and computational approaches to mechanistically analyze the molecular and cellular mechanisms controlling neuronal differentiation, migration and polarization.
Candidates should have (or expect) a Ph.D. and/or M.D. and should have a strong background in cell biology, neuroscience, or biophysics. This position is an ideal opportunity for either (1) a cell biologist well versed in quantitative live cell light microscopy whom would like to expand their research topic into neuronal cell biology or tissue morphogenesis, (2) a molecular biologist with experience in genomics approaches to understand epigenetic mechanisms of gene regulation with an interest to link that knowledge to the cell biology of nuclear organization using high resolution microscopy, or (3) a biophysics oriented candidate that would like to apply traction force measurements and finite element analysis to understand how neurons alter adhesive affinities during key steps in their motility.
To apply for this position, submit the online application, and send a letter of interest, C.V., 3 letters of recommendation, and a description of your research interests to:
David J. Solecki, PhD
Department of Structural Biology
Mail Stop 311
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105
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