Postdoctoral Research Associate

US-TN-Memphis
ID
38112
Department
Structural Biology
Faculty Member
Junmin Peng

Summary

One postdoctoral position is available for motivated candidates in the laboratory of Dr. Junmin Peng at St. Jude Children’s Research Hospital, a premier center for biomedical investigation located in Memphis, Tennessee, USA. The successful applicant will use systems biology and mathematical modeling methods to interpret temporal multi-omics datasets and to explore molecular mechanisms of common human disorders (e.g. Alzheimer’s disease and cancer). Integrated systems biology analyses of comprehensive omics data offer a systems or holistic view, for unbiased identification of central disease gene/protein networks, functional modules and master regulators. Beyond big data analysis, molecular targets of interest will be followed in subsequent hypothesis-driven studies in cellular and animal models. We will also investigate the perturbation of cellular systems by small molecule drugs that modulate the activities of these targets. The overarching aim is to develop systems biology approaches and provide novel insights into the pathogenesis and therapeutic intervention, as well as disease biomarker discovery for precision medicine (https://www.stjude.org/peng). Our publication record is available on Google Scholar (150+ publications, 17,500+ citations, http://scholar.google.com/citations?user=vFzS-awAAAAJ&hl=en, e.g. Tan et al. Immunity 2017, Lee et al. Cell 2017, Bai et al. PNAS 2013, and Xu et al. Cell 2009). Postdoctoral fellows in our group have extensive interaction with other 20+ members for career development in mass spectrometry-based proteomics and metabolomics, systems biology and independent research of human disease. Approximately 50% of postdoctoral alumni (n = 19) become principal investigators or medical doctors.

 

St. Jude is a top-ranked hospital (No. 1 Pediatric Cancer Hospital in 2017) and a world-class basic research institute with 220+ faculty members, including renowned faculty (e.g., Nobel Laureate, National Academy of Sciences, Institute of Medicine, and HHMI). St. Jude offers extraordinary resources and facility, a highly interactive environment for career development, and has been on FORTUNE magazine’s “100 Best Companies to Work For” list. St. Jude postdoctoral fellows are provided with a competitive salary, a professional development allowance, and an array of benefits, including health, dental and vision coverage, and a retirement program.

Minimum Education

The candidate shall have a Ph.D. degree in systems biology, mathematics, statistics, bioinformatics, computer science, or a related field. The candidate is expected to design algorithms and develop computational tools. Strong background in mathematical modeling for biological questions (e.g. system identification) is preferred, but prior expertise in omics technologies is not required. The candidate must have an excellent publication record and demonstrate excellent programming skill in languages such as R, C++, MATLAB, Perl, or Python. Please apply online and submit CV, three references, a brief statement regarding previous work and future goals to Dr. Junmin Peng (junmin.peng@stjude.org), Member (Professor), Director of St. Jude Proteomics Facility, St. Jude Children’s Research Hospital.

EEO

St. Jude is an Equal Opportunity Employer

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