Postdoctoral Fellowships are available in the laboratory of Dr. Hongbo Chi in the Department of Immunology, St. Jude Children’s Research Hospital to investigate cell metabolism of the immune system (immunometabolism) and its implications in cancer and other diseases. We are particularly interested in understanding the signaling network and metabolic programs mediated by mTOR and related pathways in basic T cell and dendritic cell biology. We also investigate mechanisms of tumor immunity and immunotherapy. The experimental models include genetically-modified mice and primary immune cells derived from these mice, as well as in vitro systems to explore signaling, metabolic, transcriptional and epigenetic regulation. Moreover, we use interdisciplinary strategies by integrating these immunological approaches with cutting-edge systems biology tools including transcriptomics, proteomics, metabolomics and network reconstruction. Please see the following articles (Nature 499:485 (2013); Immunity 39:1043 (2013); Nature Immunology 16:178 (2015); Nature Immunology 17:277 (2016); Immunity 45:540 (2016); Nature 548:602 (2017); Immunity 46:488 (2017); J Exp Med 214:2629 (2017)) for additional information.
St. Jude Children’s Research Hospital, a private research institute, located in Memphis, Tennessee, USA, was recently named the nation's No. 1 pediatric cancer hospital. St. Jude offers an exceptional research and training environment with state-of-the-art facilities, along with competitive salary and excellent benefits to postdoctoral fellows.
Highly motivated individuals with a recent Ph.D. in immunology, biochemistry, or cell biology, with evidence of scientific accomplishment, are encouraged to apply.
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