St. Jude Children's Research Hospital

Returning Candidates

Postdoctoral Research Associate

Postdoctoral Research Associate

Tumor Cell Biology
Job Location 
Faculty Member 
Martine Roussel

More information about this job


The Roussel Laboratory is seeking a highly motivated and creative candidate for a fully supported postdoctoral fellowship to develop potential strategies to treat medulloblastoma via the identification and chemical modification of targeted therapies and their validation in animal models and patient-derived xenografts. A fellow will have the opportunity for robust collaboration with other departments including Chemical Biology, Oncology, Hematology, Pharmaceutical Sciences, Biostatistics, Computational Biology and the Brain Tumor Program.


You will lead a project investigating:

  • Small molecule optimization by high throughput in vitro screening
  • Chemoproteomics for target identification by mass spectrometry
  • Intracellular imaging with fluorescent probes
  • Pre-clinical trials in mouse and patient-derived xenograft

You will gain extensive training and experience in high‐throughput drug screening, mammalian cell and neuronal progenitor culture, target identification by pull-down and mass spectrometry, and pre-clinical studies.

Minimum Education

The successful applicant will have a strong publication record, excellent communication skills, and a Ph.D. or equivalent in molecular biology, cell biology, biochemistry, or related field. Strong molecular and cell biology background, with an emphasis on manipulation of mammalian cells and animal models are critical for success. Applicants with experience in drug screening, target identification by mass spectrometry, and validation of small molecules in vitro and in mouse models are strongly encouraged to apply.


About St. Jude


St. Jude Children’s Research Hospital, located in Memphis, Tennessee, is one of the world’s premier research and treatment centers for childhood disease. St. Jude has been recognized by Fortune magazine as one of the “100 Best Companies to Work For” every year since 2011 and was one of The Scientist’s top 10 “Best Places to Work in Academia” for seven consecutive years. Memphis is a vibrant city in the mid-South, with a temperate climate, very active music scene, excellent restaurants, many family-friendly activities, and extremely affordable housing. St. Jude offers highly competitive stipends and benefits and actively fosters professional development. For more information, visit  


Please direct inquiries to:

Martine F. Roussel, Ph.D.


St. Jude is an Equal Opportunity Employer

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