Postdoctoral Fellowship in Genome Editing for Sickle Cell Disease

US-TN-Memphis
ID
37033
Department
Hematology
Faculty Member
Shengdar Tsai

Summary

The Tsai, Weiss, and Miller Laboratories are seeking highly motivated and creative candidates for a fully supported postdoctoral fellowship to develop potentially curative strategies to treat sickle cell disease by CRISPR-Cas gene editing of human hematopoietic stem cells.

 

You will have the opportunity to lead new projects such as:

  • Optimizing pre-clinical CRISPR-Cas gene editing strategies for induction of fetal hemoglobin in red blood cell progeny of edited human hematopoietic stem and progenitor cells
  • Developing improved genomic methods to define and measure genome-wide activity of gene editing nucleases
  • Protein engineering of CRISPR-Cas nucleases for precise gene correction

In this position, you will gain extensive experience and training in gene editing, protein engineering, and high-throughput genome biology.

Minimum Education

Successful applicants will have a strong publication record, excellent communication skills, and a Ph.D. or equivalent degree in molecular biology, cell biology, genetics, genomics, hematology, or a related area. To succeed in this position, you will have a strong molecular and cell biology background, with an emphasis on molecular cloning and genetic manipulation of mammalian cells. Applicants with experience with human hematopoietic stem cells, genome editing, next-generation sequencing, or automated liquid handling are strongly encouraged to apply.

 

Please direct inquiries to:

Shengdar Tsai, Ph.D.

shengdar.tsai@stjude.org

www.stjude.org/tsai

 

About St. Jude

 

St. Jude Children’s Research Hospital, located in Memphis, Tennessee, is one of the world’s premier research and treatment centers for childhood disease. St. Jude has been recognized by Fortune magazine as one of the “100 Best Companies to Work For” every year since 2011 and was one of The Scientist’s top 10 “Best Places to Work in Academia” for seven consecutive years. St. Jude offers highly competitive stipends and benefits and actively fosters professional development. For more information, visit www.stjude.org.

EEO

St. Jude is an Equal Opportunity Employer

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